R65.1

ICD-10Non-billable category

SIRS of non-infectious origin

Official ICD-10-CM descriptor (FY2026)

Systemic inflammatory response syndrome (SIRS) of non-infectious origin

R65.1 is a category heading, not a billable code. CMS does not accept it on a claim; report one of the more specific codes beneath it.

Excludes1

Not coded here. An Excludes1 code should never be reported at the same time as the code above it.

  • sepsis- code to infection
  • severe sepsis (R65.2)

Code first

Sequence the underlying condition before this code.

  • underlying condition, such as:
  • heatstroke (T67.0-)
  • injury and trauma (S00-T88)

ICD-10-CM FY2026 defines 2 codes beneath R65.1. See the ICD-10-CM index for what this site publishes.

Related codes in R65

Where this code sits

Parent code
R65

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Source

ICD-10-CM FY2026. Centers for Medicare & Medicaid Services (CMS) / National Center for Health Statistics (NCHS), “2026 ICD-10-CM Code Descriptions in Tabular Order” (icd10cm_order_2026.txt). Download the original file from cms.gov. Public domain (US Government work). Descriptors, billable flags and instructional notes on this page are reproduced from that file without modification. Krasyn adds no clinical guidance.

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