T80.5

ICD-10Non-billable category

Anaphylactic reaction due to serum

Official ICD-10-CM descriptor (FY2026)

Anaphylactic reaction due to serum

T80.5 is a category heading, not a billable code. CMS does not accept it on a claim; report one of the more specific codes beneath it.

Inclusion terms

  • Allergic shock due to serum
  • Anaphylactic shock due to serum
  • Anaphylactoid reaction due to serum
  • Anaphylaxis due to serum

Excludes1

Not coded here. An Excludes1 code should never be reported at the same time as the code above it.

  • ABO incompatibility reaction due to transfusion of blood or blood products (T80.3-)
  • allergic reaction or shock NOS (T78.2)
  • anaphylactic reaction or shock NOS (T78.2)
  • anaphylactic reaction or shock due to adverse effect of correct medicinal substance properly administered (T88.6)
  • other serum reaction (T80.6-)

ICD-10-CM FY2026 defines 3 codes beneath T80.5. See the ICD-10-CM index for what this site publishes.

Related codes in T80

Where this code sits

Parent code
T80

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Source

ICD-10-CM FY2026. Centers for Medicare & Medicaid Services (CMS) / National Center for Health Statistics (NCHS), “2026 ICD-10-CM Code Descriptions in Tabular Order” (icd10cm_order_2026.txt). Download the original file from cms.gov. Public domain (US Government work). Descriptors, billable flags and instructional notes on this page are reproduced from that file without modification. Krasyn adds no clinical guidance.

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