D80-D89

Certain disorders involving the immune mechanism

Certain disorders involving the immune mechanism (D80-D89) is a block within ICD-10-CM Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism. It holds 7 categories.

Includes

  • defects in the complement system
  • immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
  • sarcoidosis

Excludes1

Not coded here. An Excludes1 code should never be reported at the same time as the code above it.

  • autoimmune disease (systemic) NOS (M35.9)
  • functional disorders of polymorphonuclear neutrophils (D71-)
  • human immunodeficiency virus [HIV] disease (B20)

Categories in D80-D89

Source

ICD-10-CM FY2026. Centers for Medicare & Medicaid Services (CMS) / National Center for Health Statistics (NCHS), “2026 ICD-10-CM Code Descriptions in Tabular Order (icd10cm_order_2026.txt). Download the original file from cms.gov. Public domain (US Government work). Descriptors, billable flags and instructional notes on this page are reproduced from that file without modification. Krasyn adds no clinical guidance.

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